Ontology-Based Extraction and Summarization of Protein Mutation Impact Information

Introduction

Poster at BioNLP 2010: Ontology-Based Extraction and Summarization of Protein Mutation Impact InformationPoster at BioNLP 2010: Ontology-Based Extraction and Summarization of Protein Mutation Impact InformationNLP methods for extracting mutation information from the bibliome have become an important new research area within bio-NLP, as manually curated databases, like the Protein Mutant Database (PMD) (Kawabata et al., 1999), cannot keep up with the rapid pace of mutation research. However, while significant progress has been made with respect to mutation detection, the automated extraction of the impacts of these mutations has so far not been targeted. In this paper, we describe the first work to automatically summarize impact information from protein mutations. Our approach is based on populating an OWL-DL ontology with impact information, which can then be queried to provide structured information, including a summary.

Reference

Nona Naderi and René Witte. Ontology-Based Extraction and Summarization of Protein Mutation Impact Information. Proceedings of the 2010 Workshop on Biomedical Natural Language Processing (BioNLP 2010), pp.128-129. July 15, 2010, Uppsala, Sweden. Association for Computational Linguistics (ACL).

Bibtex entry (also for download):

@InProceedings{naderi-witte:2010:BioNLP,
  author = {Nona Naderi and Ren\'{e} Witte},
  title = {{Ontology-Based Extraction and Summarization 
            of Protein Mutation Impact Information}},
  booktitle = {Proceedings of the 2010 Workshop on 
               Biomedical Natural Language Processing (BioNLP 2010)},
  pages = {128--129},
  publisher = {Association for Computational Linguistics (ACL)},
  month = {July 15},
  year = 2010,
  address = {Uppsala, Sweden}
}

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